If someone wants something from me that she has no right to ask of, is it wrong to say no just because I do not want to give up what she wants? I said no and she was rude. Should I give in to make her happy at my discomfort and hurt?

No. You are not morally required to give someone something simply because they want it, especially if they have no rightful claim to it and giving it would cause you genuine discomfort or harm.

The Bible teaches generosity and self-sacrifice, but it also teaches wisdom, honesty, and appropriate boundaries. Christian love does not mean allowing another person to pressure, manipulate, or mistreat you. Paul says giving should be willing, “not grudgingly, or of necessity” (2 Corinthians 9:7). A coerced “yes” is not the same as freely choosing to give.

Jesus was compassionate, but He did not grant every request made of Him. At times He withdrew, refused demands, or challenged improper expectations (Mark 1:35–38; Luke 12:13–15). Saying “no” can therefore be entirely consistent with love.

Her becoming rude after you said no does not create an obligation for you to change your answer. In fact, giving in simply because someone reacts badly can teach that anger or disrespect is an effective way to get what she wants.

At the same time, your “no” should be given without cruelty or revenge. Ephesians 4:15 speaks of “speaking the truth in love.” You can be firm and still be kind.

A healthy response might be: “I understand that this matters to you, but I’m not comfortable agreeing to that. I’m not trying to hurt you, but my answer is no.”

So no, you do not have to sacrifice your peace, wellbeing, or legitimate boundaries merely to keep someone else happy. Love sometimes gives sacrificially, but love does not require surrendering to unreasonable demands.